Figure 3: (A) The effect of chronic treatment with BSO (250, 500, and 1000 mg/kg; p.o.) from the 1st day to the 21st day after surgery on the development of the mechanical allodynia; (B) the effect of acute treatment with BSO (250, 500, and 1000 mg/kg; p.o.) on the mechanical allodynia. The CCI groups received vehicles according to the treatment schedule. CCI group was given almond oil according to the same schedule. The results are expressed as mean ± SEM, n = 8 **P < 0.01, ***P < 0.01 indicate significant differences versus the CCI group. BSO, Black seed oil; CCI, chronic constriction injury.