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Figure 2: The effects of BSO on the development of neuropathic pain. The effect of chronic treatment with BSO (250, 500, and 1000 mg/kg; p.o.) from the 1st day to the 21st day after surgery on the development of heat hyperalgesia; (B) the effect of acute treatment with BSO (250, 500, and 1000 mg/kg; p.o.) on the heat hyperalgesia. The CCI groups received vehicles according to the treatment schedule. CCI group was given almond oil according to the same schedule. The results are expressed as mean ± SEM, n = 8. **P < 0.01 indicates significant differences versus the CCI group. BSO, Black seed oil; CCI, chronic constriction injury. |
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