Figure 6: The effect of oxypeucedanin and isoimperatorinon on caspase-3 activity in PC12 cells. Cells were pretreated with oxypeucedanin and isoimperatorin (80 μg/mL) for 2 h and 21 h, respectively, before exposure to DOX at 5 μM. Data are expressed as mean ± SEM of three separate experiments. *P < 0.05 Indicates significant difference compared to the control group and #P < 0.05 versus DOX-treated cells. DOX, Doxorubicin; ISO, isoimperatorin; OXY, oxypeucedanin.